Lycopene is what gives tomatoes, and several other fruits, their deep red color. But lycopene is also a powerful antioxidant that has shown remarkable effect on degenerative diseases. Tomatoes are the only major dietary source of lycopene. According to a study presented at the annual meeting of the American Association for Cancer Research (AACR), tomatoes may help reduce the risk of certain types of cancer.
Lycopene is present naturally in human plasma in greater amounts than beta carotene and other essential dietary carotenoids. This may indicates its greater biological significance in the human defense system. The researchers in P&S and Harlem Hospital evaluated the association between lung cancer and lycopene.
Investigators collected blood samples from 93 individuals with non-small cell lung cancer and also from 102 matched controls, in a case-control study. They tested tested the samples for levels of certain micronutrients, including retinol, lycopene and beta-carotene.
The researchers found no significant differences between control subjects and subjects with lung cancer. in most of the micronutrients for which they did the tests. But they did find that lung cancer patients had significantly lower concentrations of lycopene.
After adjusting for age, race, sex, drinking, smoking, vitamin supplements, occupational exposure and season, the investigators found that the group with the lowest levels of lycopene, had almost a three-fold increased risk for cancer compared with the group with the highest lycopene levels.
When the investigators evaluated current smokers, they found that the group with the lowest lycopene blood levels had four times the risk of cancer than the group with the highest lycopene levels. According to Dr. Jean G. Ford, assistant professor of medicine and principal investigator:
"We concluded from our findings that low intake of lycopene may be a risk factor for lung cancer, especially for smokers. Even though our findings are preliminary, they add to the growing body of evidence that diets rich in tomatoes and tomato products are strongly linked to a reduced risk of certain types of cancer."
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